The relationship between tumor cells and the immune system is multifaceted and this fact is reflected by the heterogeneous composition of this cluster. Our common aim is to gain a basic understanding of parameters determining how tumor cells and immune cells interact and, based on this knowledge, to develop novel strategies that may support the immune system in its fight against tumors.
Two major directions of research can be classified. On the one hand chronic inflammatory diseases like certain infections or autoimmune diseases account for an increased risk for the development of cancer. On the other hand, several types of immune cells, like NK-cells, T-cells or dendritic cells, search for and try to combat newly arising tumors in a process called immune surveillance. Corresponding to this dichotomy the cluster encompasses groups investigating host-pathogen interactions, the role of inflammation in cancer development but also cancer immune surveillance.
If you need further information or if you are interested in joining this cluster, please contact a coordinator.